The brain can use two main fuels, glucose or ketones, both of which cross the blood-brain barrier. In people who eat a diet moderate to high in carbohydrates, the brain’s main energy source is glucose. In people who eat a low carb-ketogenic diet, the brain’s main energy source is ketones.

Females, Carbohydrates, and Hormones. For a clean Paleo diet, 100 grams of carbohydrates would be equivalent to eating approximately two large sweet potatoes and 1 cup of blueberries.. I have to admit though that my leptin and insulin got fixed and I my brain worked brilliant on keto, also.

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A primary function of leptin is to act as a messenger from stored fat to the brain to provide feedback about how much fat is in storage (i.e., the status of our "reservoir" of stored energy). Leptin is secreted into the bloodstream by fat cells (adipocytes) in proportion to the amount of fat mass. More fat, more leptin secreted.

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The Leptin Rx.FAQs; Overweight, large appetite and craving carbs are signs you’re Leptin Resistant. If you are fit and in decent shape, then your reverse T3 will be elevated, also indicating you’re Leptin Resistant; STEP TWO: FOLLOW A STRICT EPI-PALEO DIET. For best results follow the Epi-Paleo diet, as outlined in Epi-Paleo Rx

The experts from The Paleo Diet weigh in! LOREN CORDAIN, PH.D. Founder of The Paleo Diet Movement, Adherence to a low-fat vs. low-carbohydrate diet differs by insulin resistance status.. Roberts MD, et al. Influence of serum leptin on weight and body fat growth in children at high risk.